Clinical Trial Opportunity

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Participants with multiple sclerosis
are needed for a research study on:

PET/CT imaging of leg muscles after walking
Researchers from the University of Colorado Anschutz Medical Campus and Colorado State University are conducting a study to investigate leg muscle function following a treadmill walking test.
You may be eligible to participate if you -
  • Have clinically confirmed diagnosis of multiple sclerosis (MS) 
  • Are between 18 and 55 years old
  • Are able to walk at least 328 feet (approximately the length of one city block) and for 15 minutes without assistance Have one leg weaker than the other
Study participation involves -
  • Approximately 2 hours of testing in a research laboratory on the University of Colorado Anschutz Medical Campus
  • Screening tests to determine eligibility include leg muscle strength, leg muscle stiffness, and a laboratory physical pre-screen exam
  • Walking test includes walking for 15 min. on a treadmill at a comfortable spee
  • Following the walking test, you will be placed in the PET/CT scanner to image your bod
  • In order to get images of your muscles, a small amount of radioactive substance will be delivered into a vein in your arm during the walking test, additionally blood tests will be performed
Goal of the study -
To find reasons for the progressive leg muscle weakness in persons with MS following physical activity, by looking at the energy used in the muscles of persons with MS and healthy subjects after walking.
Compensation will be provided to you for participating in this research.
If you are interested, please contact Jeffrey Hebert by calling 303-724-9595 or by email at This email address is being protected from spambots. You need JavaScript enabled to view it. to learn more about the study. University of Colorado Denver-Principal Investigator: Jeffrey Hebert, PhD, PT, MSCS
Colorado State University-Principal Investigator: Thorsten Rudroff, PhD
Co-Investigator: Phillip Koo, MD

This study is supported by a pilot research grant from the National Multiple Sclerosis Society Colorado Multiple Institutional Review (COMIRB) approved Protocol # 13-1407.
            Version Date: 05/27/13
8845 Wagner Street | Westminster, CO 80031 US
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