Hand Dexterity and Coordination/Weakness Coordination problems may be experienced as mild shakiness when writing, slowed or difficult handling of objects, or decreased accuracy in  a deliberate movement like hitting keys on a keyboard.  Many things can adversely affect coordination including impaired vision, weakness, numbness, spasticity (muscle stiffness), and tremors.  Weakness may prevent prolonged use of the arms and hands, or make it difficult to grasp and lift objects.