Clinical Research & Trials
At the Rocky Mountain MS Center, we know that clinical research is critical to understanding this diseases complex triggers and effects, and will lead to better treatments and ultimately the cure. The Rocky Mountain MS Center at Anschutz Medical Campus is the home of a world-class MS research program, with 22 clinical trials currently under way and many more in the planning stages. Other researchers in Colorado are also conducting vital clinical research in our community. The success of these clinical research programs depends on the broad support of the MS community in Colorado and Wyoming.
If you would like be notified when new clinical trials are added, please click HERE.
Please note that the studies listed below are being conducted at the Rocky Mountain MS Center, University of Colorado Denver Anschutz Medical Campus. You will be required to come to the study site for visits. Many of the studies are conducted at various sites around the United States and therefore if you do not reside in the Rocky Mountain Region, there may be a site in or near your area that would be more convenient. We will do our best to provide you with this information if available. You may be able to find this information using http://www.clinicaltrials.gov as well.
If you are interested in any of the studies listed below please call 303-724-4644 and provide your name, a phone number where you can be reached and the best time to reach you. Please allow 5-7 business days for a response.
Participants with multiple sclerosis are needed for a research study on: Arbaclofen (an extended release anti-spasticity investigational medication)
Purpose of the study -
Researchers from the University of Colorado Anschutz Medical Campus are conducting a clinical trial to compare the effectiveness and safety of arbaclofen extended release tablets to baclofen in MS patients with muscle spasticity.
You may be eligible to participate if you -
Study participation involves -
University of Colorado Denver-Principal Investigator: Augusto Miravalle, MD
Western Institutional Review Board (WIRB) approved Protocol # OS440-3002.
Participants with multiple sclerosis are needed for a research study on: PET/CT imaging of leg muscles after walking
Researchers from the University of Colorado Anschutz Medical Campus and Colorado State University are conducting a study to investigate leg muscle function following a treadmill walking test.
You may be eligible to participate if you -
Goal of the study -
To find reasons for the progressive leg muscle weakness in persons with MS following physical activity, by looking at the energy used in the muscles of persons with MS and healthy subjects after walking.
Compensation will be provided to you for participating in this research.
University of Colorado Denver-Principal Investigator: Jeffrey Hebert, PhD, PT, MSCS
Colorado State University-Principal Investigator: Thorsten Rudroff, PhD
Co-Investigator: Phillip Koo, MD
This study is supported by a pilot research grant from the National Multiple Sclerosis Society
Colorado Multiple Institutional Review (COMIRB) approved Protocol # 13-1407.
Version Date: 05/27/13
Participants are needed for an Exercise Research Trial for People with Multiple Sclerosis
Exercise research study involving balance and eye movement training aimed at improving unsteadiness and fatigue
You may be eligible to participate if you:
Research Study Involvement:
If you are interested in participating or have questions, please contact either Ruth or Barby:
Principal Investigator: Jeffrey Hebert, PhD, PT, MSCS
Co-Principle Investigator: Margaret Schenkman PhD, PT
Co-Investigators: Timothy Vollmer, MD, John Corboy, MD
Colorado Multiple Institutional Review Board (COMIRB) approved Protocol# 12-1114
This research study is supported by a research grant from the National Multiple Sclerosis Society
MS Volunteers Needed for Research Study
Rocky Mountain MS Center on the Anschutz Medical Campus is looking for women with relapsing-remitting, secondary-progressive or primary-progressive multiple sclerosis for a 12 -month study. The study is looking to see if there is cognitive improvement with the treatment of oral estriol plus standard MS treatment as compared to standard MS treatments plus oral placebo. There will be no patients receiving only placebo in this trial. They will all receive their standard MS treatment.
We are looking for:
You are not eligible for the study if you are pregnant, breast-feeding, smoke, or have other serious medical conditions.
If you are interested, call Barby Halliday at (303) 724-4717 for further information and a 20-minute telephone screening to determine initial eligibility for the study.
This study is being conducted by John Corboy, M.D.,
Professor, UC Denver, Department of Neurology
COMIRB# 12-1388 approved 6/17/13
Title: Brain Activity and Fatigue in Persons with Multiple Sclerosis
Purpose: A pilot study to examine the influence of changes in brain structure and function on the fatigue reported by individuals with
Main Eligibility Requirements:
Participants will be compensated for their time.
Title: A phase II, double blinded, placebo controlled, randomized study comparing rituximab induction therapy followed by glatiramer acetate therapy to glatiramer acetate monotherapy in patients with relapsing forms of multiple sclerosis.
Dr. Timothy Vollmer
COMIRB# 10-1143 Approved 01/26/2012
For more information on various clinical trials throughout the United States please visit: